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Washington, D.C. (3.5 hours)
I-270 to Frederick, MD; I-70 W to Hancock, MD; I-68 W through Cumberland to US  219 South (Exit 14A) to Deep Creek Lake (18 miles)

Baltimore, MD (3.5
I-70 to Hancock, MD, then follow same route as above from Washington, D.C.

Pittsburgh, PA via Uniontown, PA (2 hours)
US 51 to Uniontown;  US 40 E to US 219 South to the Lake

Pittsburgh, PA via Morgantown, WV (2 hours)
I-79 S to Morgantown; I-68 E to Exit 4 at Friendsville, MD; MD Route 42 S to intersection with US 219;merge onto US 219 South at McHenry (5 miles to Deep Creek Lake).
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